BRONJ

Abstract

Bisphosphonates (BPs) have been widely used in medical practice as anti-resorptive agents owing to their anti-osteoclastic action. These compounds are also used for their analgesic action and their potential anti-tumor effect. Patients treated with BPs develop ostenecrosis of jaw or maxillary bone after minor local trauma labeled as bisphosphonate related osteonecrosis of jaw (BRONJ). The etiopathogenic mechanism of this pathological condition is poorly understood. In the present case report, a case with follow up of left maxillary osteomyelitis due to BPs is presented.