Xerostomia Induced by Radiotherapy: A Review

Dr. Rupali Soni; Dr. Bhavin Dudhia; Dr. Nidhi Senta; Dr. Siddharth Chhabaria

Authors

Dr. Rupali Soni PG Student, Oral Medicine and Radiology, Ahmedabad Dental College and Hospital, Near Hare Krishna Mandir, Bhadaj Ranchodpura Road, Ahmedabad Gujarat - 382115 Author
Dr. Bhavin Dudhia Head of Department, Oral Medicine and Radiology, Ahmedabad Dental College and Hospital, Near Hare Krishna Mandir, Bhadaj Ranchodpura Road, Ahmedabad Gujarat - 382115 Author
Dr. Nidhi Senta Senior Lecturer, Oral Medicine and Radiology, Ahmedabad Dental College and Hospital, Near Hare Krishna Mandir, Bhadaj Ranchodpura Road, Ahmedabad Gujarat - 382115 Author
Dr. Siddharth Chhabaria Senior Lecturer, Oral Medicine and Radiology, Ahmedabad Dental College and Hospital, Near Hare Krishna Mandir, Bhadaj Ranchodpura Road, Ahmedabad Gujarat-382115 Author

Keywords:

Xerostomia, Radiotherapy, Salivary gland dysfunction, Head and neck cancer, Radiation-induced oral complications

Abstract

Xerostomia, or dry mouth, is a common and distressing side effect of radiotherapy in patients with head and neck cancer. Radiation therapy, while effective in tumour control, inadvertently damages salivary gland tissues, leading to reduced salivary flow and altered composition. This article reviews the anatomy and physiology of salivary glands, mechanisms of radiation-induced glandular dysfunction, clinical implications, and contemporary preventive and therapeutic strategies.

Xerostomia Induced by Radiotherapy: A Review

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