Root Biomodification The Conditioning Concept

Abstract

A critical step in periodontal regenerative therapy is to alter the periodontitis affected root surface to make it a hospitable substrate, to support and encourage migration, attachment, proliferation and proper phenotypic expression of periodontal connective tissue progenitor cells. So, the Concept of Biochemical modification has emerged as a potential therapeutic approach to the reconstruction of the periodontal unit. One of the important goals in periodontal therapy is to facilitate formation of new connective tissue attachment on the denuded root surface. This type of regeneration is described by the term 'New attachment'. It can be described as embedment of new periodontal ligament fibres on to new cementum previously denuded by the periodontal disease. The periodontium consists of a cell and tissue complex organized into basic components of cementum, periodontal ligament and alveolar bone. The challenge of regeneration is to reconstitute this complex onto the root surface.